Thiamin Deficiency Common In Hospitalized Heart Failure Patients

“Failure Patients – Results Suggest That Vitamin Supplements May Help Protect Patients 14 Jan 2006 Among patients hospitalized with heart failure, about one in three has deficient levels of thiamin, although thiamin deficiency was less common among those patients who were taking vitamin supplements, according to a new study in the Jan. 17, 2006, issue of the Journal of the American College of Cardiology. “We found that one-third of congestive heart failure patients admitted to our hospital had red blood cell levels of thiamin that were lower than normal and would suggest deficiency. In contrast to some previous studies, we did not find a relationship between the development of thiamin deficiency and the amount or duration of diuretic use and urinary thiamin excretion. In fact, what was important was that a relatively small dose of thiamin from a multivitamin was protective against developing thiamin deficiency,” said Mary E. Keith, Ph.D. from St. Michael’s Hospital in Toronto, Ontario, Canada. Dr. Keith said that heart failure may increase the body’s need for certain nutrients, including thiamin, so even patients who are eating relatively well may not be getting enough of them. At the same time, the illness may make it harder to maintain a proper diet. She said that this study helps focus attention on the role of diet in managing serious conditions, such as heart failure. “Physicians and the public have exclusively focused on drug therapy to the detriment of at least one of the foundations of good health-appropriate nutrition,” she said. Thiamin, also called vitamin B1, helps the body to digest carbohydrates and perform other functions. Like other B vitamins, thiamin is not stored in the body, so poor diet can lead to deficiency in a relatively short period of time and possibly worsen the symptoms of heart failure. Although thiamin deficiency has not been extensively studied among heart failure patients, the researchers said that there are several reasons to be concerned about the problem. For instance, many heart failure patients have poor diets, and some earlier studies have indicated that diuretic medicines prescribed to help treat the condition may increase the losses of thiamin. This study is the largest study yet of thiamin deficiency among hospitalized heart failure patients, and it included participants with various degrees of illness. The researchers, including lead author Stacy A. Hanninen, R.D., M.S. C., measured the thiamin levels of 100 consecutively admitted patients with heart failure. They also measured the thiamin levels of 50 healthy people. The heart failure patients were almost three times as likely to be deficient in thiamin as the control subjects (33 percent versus 12 percent, p = 0.007). “Our sample is quite representative of our hospitalized population of heart failure patients. We also used a direct measurement of thiamin status–the erythrocyte thiamin pyrophosphate–which is more specific than earlier assays that indirectly measured enzyme activity. Finally, our study also investigated factors” -medical news today

Magnesium is therapeutic in treating the following

Magnesium is therapeutic in treating the following

Calcium causes muscles to contract, while magnesium gives them the ability to rela
Magnesium is therapeutic in treating the following:
1. Anxiety and panic attacks- because it helps keep adrenal stress hormones under control
2. Asthma – both histamine production and bronchial spasms increase with magnesium deficiency
3. Blood clots – magnesium prevents blood clots and thins blood without side effects.
4. Bowel disease – magnesium deficiency is one of the main causes of constipation.
5. Cystitis – bladder spasms are worsened by a magnesium deficiency.
6. Depression – serotonin (mood elevator) is dependent on magnesium for its production and function.
7. Heavy metals – magnesium is essential for the removal of heavy metals such as aluminum and lead.
8. Diabetes – magnesium facilitates the production of insulin and the transfer of glucose into the cells.
9. Fatigue – magnesium deficiency affects hundreds of enzymes, and fatigue is one of the first signs of a magnesium deficiency.
10. Heart disease – The heart requires magnesium as does all muscles.
11. Hypertension, hypoglycemia, insomnia, kidney disease, migraines, nerve problems, PMS, osteoporosis, Raynaud’s syndrome, and tooth decay are all aggravated, and sometimes caused by a magnesium deficiency.
What are some examples to reduce the amount of magnesium in the body such as, exercise, sweating, stress, prescription drugs, fluoride, and calcium supplementation.
Magnesium is necessary to properly metabolize calcium, and it keeps calcium in solution in the body, so it prevents calcifications, which are quite common.
Healthy Nature Hour M-F 1pm

Healthy Nature Hour M-F 1pm

100’s of Ways Synthetic Sugar Can Ruin Your Health


In addition to throwing off the body’s homeostasis, excess sugar may result in a number
of other significant consequences. The following is a listing of some of sugar’s metabolic
consequences from a variety of medical journals and other scientific publications. Each
number is footnoted at the end.

1. Sugar can suppress the immune system.
2. Sugar can upset the body’s mineral balance.
3. Sugar can cause hyperactivity, anxiety, concentration difficulties, and crankiness in
4. Sugar can cause drowsiness and decreased activity in children.
5. Sugar can adversely affect children’s school grades.
6. Sugar can produce a significant rise in triglycerides.
7. Sugar contributes to a weakened defense against bacterial infection.
8. Sugar can cause kidney damage.
9. Sugar can reduce helpful high-density cholesterol (HDLs).
10. Sugar can promote an elevation of harmful cholesterol (LDLs).
11. Sugar may lead to chromium deficiency.
12. Sugar can cause copper deficiency.
13. Sugar interferes with absorption of calcium and magnesium.
14. Sugar may lead to cancer of the breast, ovaries, prostate, and rectum.
15. Sugar can cause colon cancer, with an increased risk in women.
16. Sugar can be a risk factor in gall bladder cancer.
17. Sugar can increase fasting levels of blood glucose.
18. Sugar can weaken eyesight.
19. Sugar raises the level of a neurotransmitter called serotonin, which can narrow blood
20. Sugar can cause hypoglycemia.
21. Sugar can produce an acidic stomach.
22. Sugar can raise adrenaline levels in children.
23. Sugar can increase the risk of coronary heart disease.
24. Sugar can speed the aging process, causing wrinkles and gray hair.
25. Sugar can lead to alcoholism.
26. Sugar can promote tooth decay.
27. Sugar can contribute to weight gain and obesity.
28. High intake of sugar increases the risk of Crohn’s disease and ulcerative colitis.
29. Sugar can cause a raw, inflamed intestinal tract in persons with gastric or duodenal
30. Sugar can cause arthritis.
31. Sugar can cause asthma.
32. Sugar can cause candidiasis (yeast infection).
33. Sugar can lead to the formation of gallstones.
34. Sugar can lead to the formation of kidney stones.
35. Sugar can cause ischemic heart disease.
36. Sugar can cause appendicitis.
37. Sugar can exacerbate the symptoms of multiple sclerosis.
38. Sugar can indirectly cause hemorrhoids.
39. Sugar can cause varicose veins.
40. Sugar can elevate glucose and insulin responses in oral contraception users.
41. Sugar can lead to periodontal disease.
42. Sugar can contribute to osteoporosis.
43. Sugar contributes to saliva acidity.
44. Sugar can cause a decrease in insulin sensitivity.
45. Sugar leads to decreased glucose tolerance.
46. Sugar can decrease growth hormone.
47. Sugar can increase total cholesterol.
48. Sugar can increase systolic blood pressure.
49. Sugar can change the structure of protein causing interference with protein absorption.
50. Sugar causes food allergies.


1. A. Sanchez, et al. “Role of Sugars in Human Neutrophilic Phagocytosis.”American Journal of Clinical Nutrition, November
1973, pp. 1180-1184
2. F. Couizy, C. Keen, M.E.Gershwin, and F.P. Mareschi.Nutritional Implications of the Interaction between Minerals. Progressive
Food and Nutrition Science 17, 1933, 65-87.
3. J. Goldman, et al. “Behavioral Effects of Sucrose on Preschool Children,” Journal of Abnormal Child Psychology. 14 1986
4. D. Behar, J. Rapoport, Berg C., Adams, and M. Cornblat. “Sugar Testing with Children Considered Behaviorally Sugar
Reactive. Nutritional Behavior 1 1984 277-288
5. Alexander Schausss. Diet, Crime and Delinquecny (Berkeley, CA: Parker House 1981)
6. S. Scanto and John Yudkin. “The Effect of Dietary Sucronse on Blood Lipids, Serum, Insulin, Platelet Adhesiveness and Body
Weith in Human Volunteers. Postgraduate Medicine Jmournal 45: 1969 602-607
7. W. Rinsdor, E. Cheraskin, and R. Ramsay. “Sucrose Neutrophlic Phagocystosis and Resistance to Disease. Dental Survey
52. 12 1976 46-48.
8. J. Yudkin, S. Kang, and K. Bruckdorfer. “Effects of High Dietary Sugar.” British Journal of Medicine 281, November 22,
1980,p. 1396.
9. Ibid.
10. Lewis GF , Steiner G Acute effects of insulin in the control of VLDL production in humans. Implications for theinsulin-resistant
state. Department of Medicine, University of Toronto, Canada. Diabetes Care 1996 Apr;19(4):390-3 R. Pamplona, M.J. Bellmunt,
M. Portero, and J. Prat. “Mechanisms of Glycation in Atherogenesis.” Medical Hypotheses 40, 1990, pp. 174-181. 4
11. A. Kozlovsky, et al. “Effects of Diets High in Simple Sugars on Urinary Chromium Losses.” Metabolism 35, June 1986, pp.
12. M. Fields, et al. “Effect of Copper Deficiency on Metabolism and Mortality in Rats Fed Sucrose or Starch Diets.” Journal of
Clinical Nutrition 113, 1983, pp. 1335-1345.
13 “Sugar and Prostate Cancer.” Health Express, October, 1982, p. 41.
14. R.M. Bostick, J.D. Potter, L.H. Kushi, et al. “Sugar, Meat, and Fat Intake, and Non-dietary Risk Factors for Colon Cancer
Incidence in Iowa Women.” Cancer Causes and Controls 5, 1994, pp. 38-52.
15. Clara Moerman, et al. “Dietary Sugar Intake in the Etiology of Biliary Tract Cancer.” lnternational Journal of Epidemiology 22,
No.2, 1993, pp.207-214.
16. J. Kelsay, et al. “Diets High in Glucose or Sucrose and Young Women.” American Journal of Clinical Nutrition 27, 1974, pp.
17. J. Lemann. “Evidence That Glucose Ingestion Inhibits Net Renal Tubular Reabsorption of Calcium and Magnesium.” Journal
of Clinical Nutrition 70, 1967, pp. 236-245.
18. H. Ed Taub, ed. “Sugar Weakens Eyesight.” VM Newsletter 5, May 1986.
19. Richard Wurtman. University of California, Berkeley, Newsletter 6, No. 3, December 1989, pp.4-5.
20 .William Dufty. Sugar Blues. (New York: Warner Books,1975.)
21. Ibid.
22. J. Lewis. “Health Briefings.” Fort Worth Star Telegram, June 11, 1990.
23. Katz RJ , Ratner RE , Cohen RM , Eisenhower E , Verme D Are insulin and proinsulin independent risk markers for
premature coronary artery disease ? Department of Medicine, Division of Cardiology, George Washington University School of
Medicine, Washington, DC 20037, USA. Diabetes 1996 Jun;45(6):736-41
24. Annette T. Lee, and Anthony Cerami. “The Role of Glycation in Aging.” Annals of the New York Academy of Science 663, pp.
6370. D.G. Dyer, et al. “Accumulation of Maillard Reaction Products in Skin Collagen in Diabetes and Aging.” Journal of Clinical
Investigation 91, No. 6, June 1993, pp. 421-422.
25. E. Abrahamson, and A. Peget. Body, Mind and Sugar. (New York: Avon, 1977.)
26. W. Glinsmann, H. Irausquin, and K. Youngmee. Report from FDA’s Sugar Task Force, 1986: Evaluation of Health Aspects of
Sugars Contained in Carbohydrate Sweeteners. (Washington, DC: Center for Food Safety and Applied Nutrition, 1986, p. 39.)
27. H. Keen, B. Thomas, R. Jarrett, and J. Fuller. “Nutrient Intake, Adiposity, and Diabetes.” British Medical Journal 6164, No. 1,
March 10, 1979, pp. 655-658.
28. T. Cleave. Sweet and Dangerous. (New York: Bantam Books, 1974, pp. 28-43.) B.G. Persson, et al. “Diet and Inflammatory
Bowel Disease.” Epidemiology 3, No. 1, January 1992, pp. 47-51.
29. T. Cleave. Sweet and Dangerous. (New York: Bantam Books, 1974, pp. 157-159.)
30. L. Darlington, Ramsey, and Mansfield. “Placebo-Controlled, Blind Study of Dietary Manipulation Therapy in Rheumatoid
Arthritis.” Lancet 8475, No. 1, February 6,1986, pp.236-238.
31. Lawrence Powers. “Sensitivity: You React to What You Eat.” Los Angeles Times, February 12, 1985.
32. W. Crook. The Yeast Connection. (Jackson, TN: Professional Books, 1984.) 3
3. K. Heaton. “The Sweet Road to Gallstones.” British Medical Journal 288, April 14, 1984, pp. 1103-1104.
34. N.J. Blacklock. “Sucrose and Idiopathic Renal Stone.” Nutrition and Health 5, No. 1-2, 1987, pp. 9-17.
35. J. Yudkin. “Dietary Fat and Dietary Sugar.” Lancet, August 29, 1964, pp. 478-479.
36. T. Cleave. The Saccharine Disease. (New Canaan, CT: Keats Publishing, 1974, p. 125.)
37. S. Erlander. “The Cause and Cure of Multiple Sclerosis.” The Disease to End Disease 1, No. 3, March 3, 1979, pp. 59-63.
38. T. Cleave. The Saccharine Disease. (New Canann, CT: Keats Publishing, 1974, p. 45.)
39. T. Cleave, and G. Campbell. Diabetes, Coronary Thrombosis and the Saccharine Disease. (Bristol, England: John Wright
and Sons, 1960.)
40. K. Behall. “Influence of Estrogen Content of Oral Contraceptives and Consumption of Sucrose on Blood Parameters.”
DiseaseAbstracts International B. 43, 1982, p. 1437.
41. W. Glinsmann, H. Irausquin, and K. Youngmee. Report from FDA’s Sugar Task Force, 1986: Evaluation of Health Aspects of
Sugars Contained in Carbohydrate Sweeteners. (Washington, DC: Center for Food Safety and Applied Nutrition, 1986, p. 39.)
42. Nancy Appleton. Lick the Sugar Habit Bones. (Garden City Park, NY: “Reaction of Monosaccharides Avery Publishing Group,
1989, with Protein: Possible Evolupp. 36-38.)
43. Schrezenmeir J III.Hyperinsulinemia, hyperproinsulinemia and insulin resistance in the metabolic syndrome. Medical Clinic,
Johannes-Gutenberg University, Mainz, Germany. Experientia 1996 May 15;52(5):426-32
44. H. Beck-Nelson., O. Pedersen, and Sorensen Schwartz. “Effects of Diet on the Cellular Insulin Binding and the Insulin
Sensitivity in Young Healthy Subjects.” Diabetes 15, 1978, pp. 289-296. 5
45. H. Keen, B. Thomas, R. Jarrett, and J. Fuller. “Nutritional Factors in Diabetes Mellitus.” J. Yudkin, ed. Applied Science, 1977,
pp. 89-108.
46. L. Gardner, and S. Reiser. “Effects of Dietary Carbohydrate on Fasting Levels of Human Growth Hormone and Cortisol.

Proceedings of the Society for Experimental Biology and Medicine 169, 1982, pp. 3640.
47. S. Reiser. “Effects of Dietary Sugars on Metabolic Risk Factors Associated with Heart Disease.” Nutritional Health 3,1985,
pp. 203-216
48. R. Hodges, and T. Rebello. “Carbohydrates and Blood Pressure.” Annals of Internal Medicine 98, 1983, pp. 838-841.Insulin,
hypertension and antihypertensive drugs in elderly patients: the Rotterdam Study. Stolk RP , Hoes AW , Pols HA , Hofman A , de
Jong PT , Lamberts SW , Grobbee DE Department of Epidemiology and Biostatistics, Erasmus University Medical School,
Rotterdam,The Netherlands. J Hypertens 1996 Feb;14(2):237-42
49. J. Simmons. “Is the Sand of Time Sugar?” Longevity, June 1990, pp. 49-53. F. Bunn, and P.J. Higgins. Significance.

Science 213, July 10, 1981, pp. 222-224. Anthony Cerarni, Helen Vlassara, and Michael Brownlee. “Glucose and Aging.

Scientific American, May 1987, p.90.
50 Nancy Appleton. Healthy Bones. (Garden City Park, NY: Avery Publishing Group, 1991.
51.Jenkins DJ , Jenkins ALNutrition principles and diabetes. A role for “lente carbohydrate”? Department of Nutritional Sciences,
University of Toronto, Ontario,Canada. Diabetes Care 1995 Nov;18(11):1491- 8″Sucrose Induces Diabetes in Cats.” Federal
Protocol 6, No. 97, 1974.
52.T. Cleave. The Saccharine Disease. (New Canaan, CT: Keats Publishing, 1974, pp. 132-133.)
53. Ibid. 54. Ruth L. Caccaro, and J. Stamle. “Relationship of Postload Plasma Glucose to Mortality with a Follow-Up.” Diabetic
Care 15, No. 10, October 1992.
55. Annette T. Lee, and Anthony Cerami. “Modifications of Proteins and Nucleic Acids by Reducing Sugars: Possible Role in
Aging.” Handbook of the Biology of Aging. (New York: Academic Press, 1990.
56. Suresh I.S. Rattan, Anastasia Derventzi, and Brian Clark. “Protein Synthesis, Post-translational Modifications, and Aging.

Annals of the New York Academy of Sciences 663, 1992, pp. 48- 62.
57.V.M. Monnier. “Nonenzymatic Glycosylation, the Maillard Reaction and the Aging Process.” Journal of Gerontology 45, No. 4,
1990, pp. 105-110.
58. R Pamplona, M.J. Bellmunt, M. Portero, and J. Prat “Mechanisms of Glycation in Atherogenesis.” Medical Hypotheses 40,
1990, pp.174-181. 59. Ibid.
60. Nancy Appleton. Healthy Bones. (Garden City Park, NY: Avery Publishing Group, 1991.
61. Annette T. Lee, and Anthony Cerami. “The Role of Glycation in Aging.” Annals of theNew York Academy of Science 663,
62. Frances Sheridan Goulart. “Are You Sugar Smart?” American Fitness, March-April 1991, pp. 34-38.
63. Ibid.
64. Ibid.
65. Ibid. Kurt Greenberg. “An Update on the Yeast Connection.” Health News and Review, Spring 1990, p. 10.
66. Frances Sheridan Goulart. “Are You Sugar Smart?” American Fitness, March-April 1991, pp. 34-38.
67. Ibid.
68. Ibid.
69. Ibid.
70. Landsberg L Insulin sensitivity in the pathogenesis of hypertension and hypertensive complications. Department of Medicine,
Northwestern University Medical School, Chicago, Illinois 60611, USA. Clin Exp Hypertens 1996 Apr-May;18(3-4):337-46
71.Jonell Nash. “Health Contenders.” Essence 23, January 1992, pp. 79-81. E. Grand. “Food Allergies and Migraine.” Lancet
8126, No. 1, 1979, pp. 955-959.
72. Larry Christensen. “The Role of Caffeine and Sugar in Depression.” The Nutrition Report 9, No. 3, March 1991, pp. 17-24.
73. Ibid.
74. Shelton Reiser, J. Hallfrisch, M. Fields, et al. “Effects of Sugars on Indices on Glucose Tolerance in Humans.” American
Journal of Clinical Nutrition 43, 1986, pp. 151-159.
75. W. Kruis, G. Forstraier, C. Scheurlen, and F. Stellaard. “Effects of Diets Low and High in Refined Sugars on Gut Transit, Bile
Acid Metabolism and Bacterial Fermentation.” Gut 32, 1991, pp. 367-370.
76. John Yudkin. “Metabolic Changes Induced by Sugar in Relation to Coronary Heart Disease and Diabetes.” Nutrition and
Health 5, No.1-2, 1987, pp. 5-8.
77. Ibid.

78.Craft S , Newcomer J , Kanne S , Dagogo-Jack S , Cryer P , Sheline Y , Luby J , Dagogo-Jack A, Alderson A Memory
improvement following induced hyperinsulinemia in Alzheimer’s disease. Department of Psychology, Washington University, St.
Louis, MO 63130, USA. Neurobiol Aging 1996 Jan-Feb;17(1):123-30

74. Christensen, Larry, “The Role of Caffeine and Sugar in Depression,” THE NUTRITION REPORT 9 NO. 3 (March 1991):
75. Ibid.
76. Cornee, J. et al., “A Case-control Study of Gastric Cancer and Nutritional Factors in Marseille, France,” EUROPEAN
JOURNAL OF EPIDEMIOLOGY 11, (1995): 55-65. JOURNAL OF EPIDEMIOLOGY 11, (1995): 55-65.
77. Yudkin, J. SWEET AND DANGEROUS. New York: Bantam Books, (1974): 129
78. Yudkin, John, SWEET AND DANGEROUS. New York: Bantam Books, (1974): 141
79. Reiser, Shelton, Hallfrisch J, Fields M, et al., Effects of Sugars on Indices on Glucose Tolerance in Humans,”AMERICAN
80. Ibid.
81. Kruis, W., Forstraier, G., Scheurlen C., and Stellaard F., “Effects of Diets Low and High in Refined Sugars on Gut Transit,
Bile Acid Metabolism and Bacterial Fermentation, GUT 32 (1991): 367-370.
82. Bostick R. M., Potter, J. D., Kushi L. H., et al, “Sugar Meat, and Fat Intake, and Non-dietary Risk Factors for Colon Cancer
Incidence in Iowa Women,” CANCER CAUSES AND CONTROL 5 (1994):38-52.
83. Persson B. G., Ahlbom, A., and Hellers, G., EPIDEMIOLOGY 3n no.1 (1992): 47-51.
84. Yudkin, John, “Metabolic Changes Induced by Sugar in Relation to Coronary Heart Disease and Diabetes,” NUTRITION
AND HEALTH 5, no. 1-2 (1987): 5-8.
85. Ibid.
86. Blacklock, N. J., “Sucrose and Idiopathic Renal Stone,” NUTRITION AND HEALTH 5, no. 1-2 (1987): 9-17. Curhan, Gary et
al, “Beverage Use and Risk for kidney Stones in Women, ANNALS OF INTERNAL MEDICINE, 1998, 128: 534-340.
87. JOURNAL OF ADVANCED MEDICINE, 1994 7(1): 51-58
88. Ibid
89. Ibid
90. POSTGRADUATE MEDICINE ,Sept 1969: 45(527):602-07. 91. Moerman, Clara J. etc., INTERNAL JOURNAL OF
EPIDEMIOLOGY April 1993:22(2)207-214.
92. Ibid. 93. JOURNAL OF NUTRITION 1997; 127: 1113-1117.
94. Ibid.
95. R. M. Bostick, J. T. Potter, et al. “Sugar, Meat and Fat Intake, and Non-Dietary risk factors for Colon Cancer Incidence in
Iowa Women.” CANCER CAUSES CONTROL, 5, 38-53, 1994.
96. Ibid.
97. JOURNAL OF NUTRITION, 127, 1997; 1113-1117.
98. Ibid.
99. Moerman, Clara et al.,”Dietary Sugar Intake in the Etiology of Biliary Tract Cancer,” INTERNATIONAL JOURNAL OF
EPIDEMIOLOGY 22 no. 2 (1993): 207-214.
100. “Sugar, white floor Withdrawal Produces Chemical Response,” THE ADDICTION LETTER (July 1992):4.
101. Ibid.
102. THE EDELL HEALTH LETTER Sept ’91; 10:7(1)
103. Bernstein, J, et. al, “Depression of Lymphosyte Transformation Following Oral Glucose Ingestion.” AMERICAN JOURNAL
106. JOURNAL OF ABNORMAL CHILD PSYCHOLOGY, 12/86, Vol. 14, No. 4: (567-577).
107. PEDIATRICS RESEARCH 38, 4, (1995): 539-542.
108. Makinen KK; Hujoel PP; Bennett CA; Isokangas P; Isotupa K; Pape HR Jr; M?akinen PL, “A Descriptive Report of the
Effects of a 16-month Xylitol Chewing-gum Programme Subsequent to a 40-month Sucrose Gum Programme.” CARIES RES,
32(2):107-12 1998
The list was contributed by Nancy Appleton, Ph.D. who has a web site at
She is also the author of the book Lick The Sugar Habit